Though its permanent collection is a who’s who of modern Spanish art, including major works by Picasso—his Guernica is the museum’s Mona Lisa—Miró, Dalí, Eduardo Chillida, and Antoni Tàpies, the Reina Sofía is also a major contemporary art institution both within and outside its Jean Nouvel-designed walls. Head to the museum for its contextualized permanent collection of Spanish and international masters, and then go to the Parque del Retiro to check out the exhibitions at the Palacio de Cristal and Palacio de Velázquez.

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