If you’re looking for a serene spot to gather your thoughts before climbing Machu Picchu, hiking Sacred Valley, or from which to explore historic Cusco, look no further than Inkaterra La Casona (it’s built on ancient Inca training grounds, after all). It’s a Relais & Châteaux hotel (the first in Peru), so even though it’s housed in a 16th century mansion, the five-star amenities—heated floors, an eco-conscious Yaku spa—are plentiful. The 11 guest rooms are strategically placed overlooking a private courtyard and done up in traditional Peruvian style (Colonial furnishings, handwoven tapestries). The house restaurant serves up traditional Peruvian delicacies and delicious breads. For breakfast, the eggs Benedict are made to order and the staff will gladly pack a to-go picnic if a day of sightseeing is on the agenda.

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