Even if you aren’t staying at the new(ish) and gorgeous Mandarin Oriental, stop by for an aperitivo. You’ll probably be in the neighborhood at some point, since the hotel is around the corner from La Scala and a short walk from the Duomo. The courtyard setting is glamorous but relaxed, located in the center of a restored 18th-century palazzo. The spa is also worth a look—and a treatment since booking a treatment means access to the indoor swimming pool. Go for the Oriental body scrub, which uses oil infused with essences of tropical Ginger, frankincense, and mandarin.

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