Rooms at the Four Seasons occupy both an opulent restored palazzo and a converted sixteenth-century convent. This is Florence at its most grand: The hotel could almost double as a museum, filled with original works of art, antiques, frescoes, and decorative stucco. The setting—eleven acres of shaded, manicured gardens—is blissfully peaceful and quiet, especially after a busy day exploring the Uffizi galleries and the Duomo (a fifteen-minute walk away). Fittingly, the spa uses products from Santa Maria Novella, the Florentine beauty company, in its own stand-alone, ten-treatment-room building, and the twenty-seven-meter lap pool is heaven on hot summer afternoons. There’s even a Michelin-starred restaurant, Il Palagio, a formal dining room with vaulted ceilings and views of the garden that specializes in pasta and seafood, with an emphasis on locally sourced ingredients.

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