Part of the prestigious Firmdale group, The Soho Hotel is situated on a quiet street in what is an otherwise bustling neighborhood. Each of the 96 surprisingly spacious rooms have been individually decorated—unheard of for a hotel of this magnitude—but all share a decidedly English mix-and-match aesthetic (florals and stripes here, ikats and plaids there). In the lobby, the eclectic vibe translates to a giant Bottero cat, more print-on-print action, and lots of floor-to-ceiling windows. Stop by The Refuel Bar for an evening cocktail or afternoon tea service.

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