Fitzrovia

Portland strikes the perfect balance between casual and formal in Fitzrovia. It’s relaxed enough for a midweek dinner when you’re in jeans, but sophisticated enough for a nice evening out with your parents. The food is a kind of New British, which really means the best of Brit ingredients dressed up with modern trends, like fermentation and smoking. Cornish mackerel comes with preserved cucumbers and green strawberries, the smoked pigeon with baby English radishes, and the little starter of plate of baby pickled vegetables—intended to just be an accompaniment—was a standout. Given that there’s an option to order as much as you want off the menu for sixty-five pounds per person, it would seem unreasonable not to. Come hungry.

Yotam Ottolenghi has opened yet another restaurant that Londoners cannot get enough of (his seventh). This time it’s in Fitzrovia—a neighborhood that, until recently, was a kind of a culinary wasteland. The addition of Rovi has changed all that. The magic here lies in the fresh, vegetable-centric dishes slathered in all manner of Israeli and Palestinian sauces and a bright, cheerful dining room with high ceilings and red banquettes. The wine list is stellar and features some rarely seen Palestinian labels.

Entering this all-white spa inside the Sanderson feels a bit like walking through a cloud (there are giant, billowing curtains). Inside, there are Reiki adjustments and enzyme facials, custom massages and luxurious manicures. Best of all, you can book a one-on-one acupuncture, sound fork, and facial session with clean-beauty genius (and founder of one of our favorite brands) Annee de Mamiel. The rejuvenating treatment, which changes seasonally, includes a craniosacral massage, gua sha, and a custom herbal mix that is ground into a mask.

Meraki is the latest from Arjun and Peter Waney, the duo behind three of our other London favorites: Zuma, Coya, and Roka. The kitchen specializes in region-specific small bites, like salty cured fish roe and tomatoes from Santorini. In terms of décor, the look is clean and contemporary—not a whiff of the traditional taverna—which makes Meraki great for more buttoned-up lunches and dinners. In other words: This is not the spot for a raucous family meal with kids. Xenia (Greek hospitality) is key here, and the wine list is exciting, heavy on Aegean labels you won't see elsewhere. Everything on the menu is really well prepared; particular standouts include the dolmades served with a rich, lemony, egg yolk emulsion, and the barrel-aged feta, which is somehow creamy, salty, sour, and sharp all at the same time.

The coffee here is among the best in a city of good coffee. The dark walls, neon signs, subway tiles, and modern, low-hanging lamps make for an appealing interior. Best of all, the high bench seating is actually comfortable and encourages you to settle in and maybe drink more caffeine than you really need. You can offset it with one of the great salads. It’s a nice respite in a city that has adopted a duck-in, duck-out coffee shop philosophy.

It took a while for one of London's most popular—and hardest to book—restaurants to expand, but it finally has and this new venture from Honey & Co. couldn't be more true-to-style fantastic. For one, there's way more room at their new, characteristically pared-back dining room for the droves of fans, and for two, they've added a grill—hence the name. You can expect a whole new selection of their seasonal and varied mezze dishes along with a grill-centric take on the mains. Expect kofta, shish, kebabs, bbq, and the like, though there are too many incredible dishes to call out as favorites. Much like its predecessor, this will be a spot to go back to time and again. Honey & Co diehards will be glad to know their famous "cheesecake" made it onto the menu for dessert.

Much like its sister restaurant Portland down the street, the somewhat austere, casual interiors belie the exquisitely prepared dishes that appear on the table. The idea here is to order a few plates to share from each category on the menu and they'll appear in no particular order as they're churned out of the kitchen. Here, everything from the halibut and herring caviar crudo to the seasonal vegetable plates are beautifully served and thought out. And because this was once a pizzeria, they've kept the oven and mastered the art, turning out beautiful pizzas and some hearty oven-baked meat dishes.

For Honey & Co. fans and newbies alike, this is a dream delicatessen packed with Middle Eastern specialty goods, fresh produce, house-made spice mixes, and vernacular kitchen essentials. Just across the street from the original, in a bright space with yellow tiles and a counter packed with co-founder Sarit's wonderful pastries, plus many of their mezze dishes for takeaway, a visit to this spot can quickly and dangerously become a habit.

From Will Lander of the Quality Chophouse fame and Daniel Morgenthau of 10 Greek Street comes this sleeper hit of a restaurant, tucked away on a quiet street in Fitzrovia. In a small dining room with almost no decoration beyond its pretty, dangling lights and the bustling open kitchen, comes some of the most inventive, beautifully presented cuisine in town, where seasonal vegetables are the stars. Order a few plates to share or go for the tasting menu for the whole table—you're in good hands here.

Owned by famed fashion photographer, Nick Knight, this gallery-film studio-shop has a conceptual take on fashion. While the studio's bread and butter is cutting-edge fashion video, it's also something of a clubhouse for London's fashion intelligentsia, where designers like Gareth Pugh, Mary Katrantzou, and Giles Deacon show their work first. During LFW, it's also a major hub, hosting talks, parties, etc.