The Whitney Museum of American Art
99 Gansevoort, Meatpacking District
The Whitney—a long-time doyenne on the UES—shut its doors and moved to the Meatpacking District, where it sits in a Renzo Piano–designed building at the southern end of the High Line. The Whitney decamped because of space constrictions uptown, a situation that's now eased by its 200,000 square feet. (The Metropolitan Museum of Art has taken over the Whitney's previous Marcel Breuer–designed home at Madison and 75th.) Bonus: It's open until 10 p.m. on the weekends.