Centro Historico

Establishment neighborhood
Mercado Lagunilla
Corner Rayón & Allende, Centro Histórico
On the same site since colonial times, the Lagunilla is one of the biggest covered markets in the city, selling food, furniture, and cheap clothing. On Sundays, though, things get a little more interesting when antique dealers and casual vendors set up on the streets surrounding the market. Though there's a lot of junk to sift through, and a good number of stalls selling pirated goods, there are some treasures to be found—costume jewelry, retro sunglasses, old-school 50's kitchen goods, and more. Plus, the torta and cold-pressed juice stand right inside one of the main entrances into the antiques area is awesome. You'll want to have your wits about you, though, as the market and its surrounds do harbour the occasional pick-pocket.
Av Francisco I. Madero 4, Centro Histórico
Sanborns is a kind of upscale generalist marketplace: You can get your prescription filled just as easily as you'll find toys, books, magazines, and a decent meal at the cafeteria. The chain—owned by billionaire Carlos Slim—is ubiquitous in the city, but its branch in the Centro Histórico is something special. Housed in the historic Casa de los Azulejos, an 18th-century palace covered in tiles, it's simply one of the most beautiful buildings in the city. Meanwhile, inside the cafeteria, where the Mexican intelligentsia used to hang out in the 50's and 60s, milkshakes and club sandwiches are served up by women in kitschy, old school uniforms. And then there's the dining room, covered in old frescoes and historic photographs (it was once also the National Jockey Club).
St. Regis Mexico City
Paseo de la Reforma 439, Centro Historico
This is one of the more recently opened hotels in the city, and definitely among the splashiest: For starters, it's one of the few skyscrapers down one of the city's main arteries, Paseo de la Reforma, which means the city views from the inside the hotel are pretty phenomenal. We also hear service is on point, beginning with a glass of champagne at check-in, and traditional butler service throughout your stay. Rooms are beautifully appointed in plush, contemporary furnishings in a subtle palette of greys and pastels. Plus, the Remede Spa is where locals in the know book in for a pamper, and the adjoining pool boasts amazing views. It's basically exactly what you'd expect from a St. Regis anywhere in the world, the only disadvantage being that it lacks a sense of local quirk and color (though there's plenty of that outside the glass doors).
Four Seasons Mexico City
Paseo de la Reforma 500, Centro Historico
You pretty much know what to expect from a Four Seasons anywhere in the world, which is top-notch service, beautifully appointed, if slightly trad, interiors, and all the hotel amenities you could ask for. This Four Seasons is no exception, and its location in a stunning colonial-style building right on Paseo de la Reforma adds plenty of local charm. There are 240 individually decorated rooms, featuring tastefully chosen Mexican art and design items. Plus, the gorgeously landscaped patio—a common feature in colonial architecture—is where you'll want to spend most of your time in the hotel, either in the pool or having breakfast al fresco. For families traveling with kids, this is probably the best bet, with child-proofed rooms on request, age-appropriate toys, and games provided on arrival, and chauffeur services and city tours to book directly from the concierge.