Palazzo Barberini
Via delle Quattro Fontane, 13, Trevi
A light-filled, 17th-century baroque palace museum that provides the most gorgeous backdrop for the art it houses. Seriously, you can spend hours here reveling in the building's details–and gardens–even before you start to pore over the National Gallery of Ancient Art collection. The giant ceiling of clouds and swirling figures by Italian painter-architect Pietro da Cortona are epic. Just around the corner from the Quattro Fontane, its central location makes it easy to get to.