Lungotevere delle Armi, 22, Prati
On the banks near Piazza del Popolo, Anna Fendi’s Villa Laetitia has twenty guest rooms, each one paying a quiet homage to one of the brand’s inner circle, be it its founder Adele or designer Karl Lagerfeld. As a result, each room is wholly unique, thoughtfully appointed with a mix of vintage pieces from Fendi’s personal collection of 19th- and 20th-century furniture, lighting, and artwork. (Look for a Mies van der Rohe sofa, paintings by Enrico Castellani, sketches on the walls by Dior and Saint Laurent.) Kitchenettes are kind of a thing throughout Europe, so each room has one (these are very modern), and most rooms have their own private terrace. For families traveling, bilingual babysitters are available upon request, and the ace general manager, Giulio Delettrez Fendi, can do everything from arrange a picnic basket for an afternoon in the park to set up bike rentals to explore the city.