Union Square

If we were to dream up the ideal, minimalist urban loft, the Palihotel—nestled right by heart-of-the-action Union Square—is it. Worn white brick walls, low-to-the-ground beds with warm striped throws, stylish mid-century-style chairs, and copper light fixtures distinguish the roomy spaces, and, like its sister properties, this outpost is sympathetic to the existing neighborhood style with its imposing, Mission Revival-style façade. Inside, though, soft pastel colors, plenty of stripes, and vintage-looking floral patterns adorn the common areas (which feel made for the freelance traveler who needs to bust out emails but appreciates pretty surroundings and quick service). Foodwise, Fisher Loft on the second floor is the kind of spot you check out for breakfast and come back for dinner: the burgers, jammy eggs, frisée salad, and (if you’re feeling extra) caviar service are menu standouts.

While we're partial to this airy space because it’s set up mere steps from our San Francisco goop MRKT, the semi-private, private, and group class menu, which ranges from Pilates to barre to yoga, really is one of the best in town. They also offer one-on-one fascial stretch therapy—pretty game changing for anyone discovering the joys of fascia.

Before adding a bricks-and-mortar location last year, the guys at Del Popolo were slinging pies out of their now-famous mobile pizzeria. Why famous? Other than the killer Neapolitan-style pizzas, which range from classic Margherita to a honey-spiked potato pie, it’s the ingenious use of a converted shipping container fastened onto a Freightliner truck in place of a standard food truck that got people talking. And lucky for us all, even with the free-standing restaurant (they tacked on some antipasti dishes and a pretty badass wine list to the restaurant menu), they’re still serving pies on the go all over the city out of the mobile pizzeria that started it all.

In a city that's known for great seafood, Farallon has been a go-to spot for fish and shellfish for almost 20 years now. It's sort of an old-school joint at this point, but the oyster menu is miles-long, and the dinner options always include a great lobster dish and excellent grilled fish. Décor-wise, they’re famous for the jellyfish lounge, where jellyfish lamps hang from the ceiling and the mezzanine level itself is shaped like the creature. While it;s a little bit over-the-top, you have to appreciate the lengths they took to make the space unique and special. The private rooms here are decorated in the same fantastical style, and they've been around long enough to appreciate the value of having an event planner on staff, which always makes things easier.

At over 100 guest rooms, Zetta is a pretty big operation (it's a member of the Viceroy family, so expect a certain level of sceney-ness), but thanks to so many welcoming touches and one-of-a-kind local art sprinkled throughout, it feels totally boutique. The guest rooms are particularly well equipped to accommodate business travelers with customizable desk spaces and high-tech gadgetry throughout.

This gem celebrated its 100th birthday a couple of years ago (it did receive a Philippe Starcke makeover in the interim) making it particularly good time to book a stay. In the famously ornate lobby you'll find furniture pieces by Ray and Charles Eames and Salvador Dali; the standard rooms while on the tight side make up for it in comfort and beautiful pastel-hued décor. Downstairs, the plush Redwood Room is perfect for drinks and snacks at the stretch bar which lent the local-approved lounge its name.

Jeffrey Fraenkel opened his eponymous gallery when he was just 24, and over the course of the last 35 years has built his brand as one of the best photography galleries in the country. With a formidable list of artists (he's shown everyone from Sol LeWitt to Diane Arbus, and he handles the estate of Garry Wineograd) and a slew of loyal collectors, he's had an enormous influence on many significant photography collections in the city.

There are now ten locations strong in the bay area, with cafés in the Ferry Building, Hayes Valley, Heath Ceramics, Market Square, Mint Plaza, and on Sansome. There are two locations in Oakland, on Broadway and Webster St. Perhaps the most groundbreaking of their brews is the chicory-spiked New Orleans cold brew, which comes in a handy single-serving carton. They also make a pretty great granola in-house while the SFMOMA rooftop location is home to Chef Caitlin Freeman’s modern art desserts. Think: a loaf cake made to look like a Mondrian painting and cookies inspired by Richard Serra’s sculptures.

There are locations peppered throughout L.A., NYC, and even Tokyo, but Blue Bottle coffee will forever be synonymous with San Francisco, the city that started it all. Perhaps the most groundbreaking of their brews is the chicory-spiked New Orleans cold brew, which comes in a handy single-serving carton. They also make a pretty great granola in-house while the SFMOMA rooftop location is home to Chef Caitlin Freeman’s modern art desserts. Think: a loaf cake made to look like a Mondrian painting and cookies inspired by Richard Serra’s sculptures.

This elegant and airy space right in the middle of downtown San Francisco is ideally situated for walking around the heart of the city. There are also the Yerba Buena gardens nearby and a stunning lap pool inside the hotel for when you need a break from sightseeing (there's also a full-on Equinox gym). It's definitely one of the city's best hotels (if not its best).