Dogpatch

As one of the pioneers of the vibrant microbrewery culture in San Francisco, Dave McLean has been passionately making craft beer for more than 15 years. His pub in Haight Ashbury is a cozy place to sample their wide selection, and their Sunday brunch comes with a beer pairing for brave souls. McLean used to keep all of his brewing equipment in the basement underneath the pub, but after outgrowing that space last year, he moved production to an enormous converted warehouse in Dogpatch. The tasting room in the shiny new brewery offers up some wickedly good BBQ and stays open until 2am on weekends.

Focusing primarily on Belgian and Japanese designers (Engineered Garments, Dries Van Noten, Comme des Garçons), the long-standing MAC is one of the city's primary destinations for edgier labels. It's enduring power probably has something to do with the owners, a brother-and-sister team with a seemingly bottomless well of design knowledge which they pass onto their employees and customers. The original location is in Hayes Valley.